The Effects of Cannabis (Marijuana) on the Brain & Body
Huberman Lab
<p>In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one’s propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents.</p><p>For the full show notes, visit <a href="https://hubermanlab.com/the-effects-of-cannabis-marijuana-on-the-brain-and-body/" rel="nofollow">hubermanlab.com</a>.</p><h2>Thank you to our sponsors</h2><p>AG1 (Athletic Greens): <a href="https://athleticgreens.com/huberman" rel="nofollow">https://athleticgreens.com/huberman</a></p><p>LMNT: <a href="https://drinklmnt.com/huberman" rel="nofollow">https://drinklmnt.com/huberman</a></p><h2>Supplements from Momentous</h2><p><a href="https://www.livemomentous.com/huberman" rel="nofollow">https://www.livemomentous.com/huberman</a></p><h2>Huberman Lab Premium</h2><p><a href="https://hubermanlab.com/premium" rel="nofollow">https://hubermanlab.com/premium</a></p><h2>Timestamps</h2><p>(00:00:00) Cannabis (Marijuana)</p><p>(00:005:02) Sponsor: LMNT</p><p>(00:07:03) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety</p><p>(00:15:08) Cannabis Strains, Psychoactive Compounds: THC & CBD</p><p>(00:19:34) Sativa vs. Indica, Stimulant vs. Relaxation Effects</p><p>(00:25:55) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains</p><p>(00:31:56) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1)</p><p>(00:35:18) Sponsor: AG1</p><p>(00:40:35) THC, CBD vs. Endogenous Cannabinoids, Dependence</p><p>(00:43:14) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function</p><p>(00:53:07) Biological Effects of Cannabis</p><p>(00:56:29) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia</p><p>(01:04:58) Cannabis Indica & Subjective Effects, Memory, Dosage</p><p>(01:09:41) Brain Areas Affected by THC & CBD, Side Effects</p><p>(01:16:08) Creativity: Convergent vs. Divergent Thinking & Dopamine</p><p>(01:26:41) Does Cannabis Increase Creativity?</p><p>(01:35:08) Chronic Cannabis Use & Changes in Speech Patterns</p><p>(01:46:46) Cannabis & Libido, Dopamine & Prolactin</p><p>(01:56:55) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility</p><p>(02:06:53) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences</p><p>(02:10:06) Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development</p><p>(02:18:13) Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance</p><p>(02:25:57) Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis</p><p>(02:34:36) Adolescent Cannabis Use: Brain Development & Mental Health Disorders</p><p>(02:41:44) Cannabis & Pain Management, Divergent Effects of Cannabis</p><p>(02:44:54) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn</p><p> Title Card Photo Credit: <a href="https://www.blabacphoto.com/" rel="nofollow">Mike Blabac</a></p><p><a href="https://hubermanlab.com/disclaimer/" rel="nofollow">Disclaimer</a></p>